The potency of Cannabidiol, or any ligand, is a complex interplay between its “ligand efficiency” and its “bioactivity” or binding affinity.

“Ligand efficiency” refers to the ability of Cannabidiol, the ligand, to produce a biological response of quantitative magnitude. This response may be as an “agonist” (positive response), an “antagonist” (blocks the agonist) or “inverse agonist” (opposite response of the agonist).

There are 22 different ways CBD is known to work (so far) in the human body (click mechanisms-of-cbd).